User Rating: 0 / 5

Star InactiveStar InactiveStar InactiveStar InactiveStar Inactive

Brief Project Summary

The Zimbabwe Vitamin A for Mothers and Babies project  (ZVITAMBO) is a randomized placebo controlled clinical trial among 14,110 mother-infants pairs to determine the impact of administering single oral doses of vitamin A to mothers and neonates in the immediate post partum period on three outcomes:

·       Infant mortality

·       Mother to child HIV transmission during breast feeding

·      Maternal HIV infection during the post partum year.

ZVITAMBO is a collaborative study between The University of Zimbabwe, the Harare City Health Department, The Montreal General Hospital Research Institute and The Johns Hopkins Bloomberg School of Public Health. 

User Rating: 0 / 5

Star InactiveStar InactiveStar InactiveStar InactiveStar Inactive

The ZVITAMBO Vitamin A trial was conducted between 1997 - 2001 which corresponded to the peak of the HIV epidemic in Zimbabwe.  When the trial began, there were no public sector HIV testing and counseling services available in the country so ZVITAMBO trained the 90 nurse-midwives employed by the trial in this skill.  At the end of the trial, the ZVITAMBO staff wanted to use these skills to support the newly formed National Program for PMTCT.  Funding was sought and awarded from Canadian International Development Agency from October 2001.  Initially, ZVITAMBO offered technical assistance to hospitals wishing to incorporate, into their regular services, work directed at preventing mother to child transmission of HIV. ZVITAMBO started work with St Theresa's Hospital (Roman Catholic, Dominicans) in Chirumhanzi (Midlands), then took on a group of three mission hospitals (RC and Elim Pentecostalist) in Nyanga North in October 2002, another group of three mission hospitals (RC and Anglican) in Mutasa District in July 2003. Towards the end of 2003 we began training and "jumpstarting" the three Methodist hospitals of Mutambara (Chimanimani District), Nyadiri (Mutoko) and Old Mutare (Mutasa).

Beginning in 2005, ZVITAMBO began supporting PMTCT at the district level.

Key services supported were:

 1. HIV counseling and testing for antenatal women and their husbands.

2. Infant feeding education and counselling for all couples (HIV positive, negative, and of unknown status).

3. Nevirapine prophylaxis for HIV positive women and their infants.

4. Cotrimoxazole prophylaxis for pregnant women with clinical AIDS and for babies born to HIV+ women.

5. Infant HIV testing (by PCR) at 6 months.

 

Finally, ZVITAMBO team members played an active role in the PMTCT Partnership Forum. 


 

User Rating: 0 / 5

Star InactiveStar InactiveStar InactiveStar InactiveStar Inactive

Zvitambo is a non-profit organization working to improve infant and maternal health in Zimbabwe, and to disseminate our findings to improve health globally. We conduct research and provide technical support and education to reduce the burden of malnutrition and infectious diseases.

Zvitambo was initially formed to conduct a trial of 14,110 mother-infant pairs assessing the impact of vitamin A supplementation on mother-to-child-transmission (read about this project here). Within that trial, we also developed an intervention to inform and support women about infant feeding in the context of HIV. After the completion of the vitamin A trial, Zvitambo expanded and became a non-profit company that conducts multiple projects funded by national and international donors.

Our work is multi-disciplinary, and encompasses technical expertise in nutrition, water, sanitation & hygiene, HIV surveillance, prevention and treatment, and health systems strengthening. Zvitambo has cutting edge research infrastructure that includes a data management center and laboratory.

We are legally registered as a non-profit company with the Ministry of Justice of Zimbabwe, and operate under two Memoranda of Understanding with the government, one with the Ministry of Higher and Tertiary Education, and the second with the Ministry of Health and Child Welfare.

About Zvitambo

The Zvitambo Institute for Maternal and Child Health Research is a multidisciplinary Zimbabwean organization that has developed and attracted expertise in various areas of biomedical and applied research and programming in the areas of maternal health, child health and growth, immunology, HIV/AIDS, nutrition, food security and livelihoods, WASH and counseling

Read more

Join Mailing List

Sign up for the latest updates from Zvitambo Institute for Maternal & Child Health Research.

Contact Zvitambo

16 Lauchlan Ave
Meyrick Park
Mabelreign
Harare
Zimbabwe

Tel : +263 4 306056 / 306259 /306028
Fax : +263 4 311069
Email : administrator@zvitambo.co.zw